NMN vs Niacine - Wat is het verschil tussen deze supplementen?

NMN vs Niacin - What is the difference between these supplements?

Niacin, also known as vitamin B3, is an essential vitamin that plays an important role in our body. Niacin not only helps lower cholesterol but also contributes to improving skin health. Niacin is important for converting food into energy and supports numerous cellular functions.

On the other hand, we have NMN, or Nicotinamide Mononucleotide, a relatively new and popular supplement. NMN is a precursor of NAD+ (nicotinamide adenine dinucleotide), a co-enzyme that is important for energy metabolism and the health of our cells. NAD+ plays a crucial role in supporting metabolism and repairing damaged DNA. Although both niacin and NMN naturally occur in our bodies, they have different functions and are involved in various processes. In this blog, we will tell you more about the differences between NMN vs niacin, their benefits, and why they are important for our health.

What is Niacin?

Wat is Niacine

Niacin is a form of vitamin B3. It is a water-soluble vitamin that is extremely important for our body. As a water-soluble vitamin, niacin cannot be stored in the body and must be regularly consumed through diet to prevent deficiencies.

Niacin is found in various foods, including meat, fish, whole grain products, and some vegetables. Interestingly, the body can also produce niacin itself from the amino acid tryptophan, which is present in protein-rich foods such as chicken, turkey, and dairy products.

There are two main forms of niacin: nicotinamide and nicotinic acid. Both forms are converted in the body and perform important functions. In food and supplements, niacin is mainly present as nicotinamide. Nicotinamide is often used because of its milder effect on the body and lower chance of side effects compared to nicotinic acid. Nicotinic acid can sometimes cause a niacin flush, which is a temporary redness and warm feeling in the skin.

Niacin function and why we need it

Niacin plays a central role in various biochemical processes that are essential for our health. The function of niacin is versatile, and it is involved in diverse physiological functions. One of the most important functions of niacin is providing energy to the body. Niacin is a component of the coenzymes NAD and NADP, which are essential for energy metabolism. These coenzymes help convert carbohydrates, fats, and proteins into energy, giving the body the fuel it needs to function.

Additionally, niacin plays a role in the production of fatty acids in the body. Fatty acids are needed for the construction of cell membranes and the production of hormones. Niacin is therefore indirectly involved in maintaining cell structures and hormonal balance.

Another important benefit of niacin is that it can help lower LDL cholesterol and triglycerides, while simultaneously increasing HDL cholesterol. This balance helps reduce the risk of cardiovascular diseases. Lowering LDL cholesterol (the 'bad' cholesterol) and triglycerides helps prevent plaque formation in the arteries, while higher HDL cholesterol (the 'good' cholesterol) helps remove excess cholesterol from the bloodstream.

Niacin also plays an important role in the health of the skin, nervous system, and digestion. It supports the production of new skin cells, which is essential for maintaining healthy skin. Moreover, niacin contributes to the functioning of the nervous system by supporting nerve impulses and helping to maintain a well-functioning digestive system.

What is NMN?

NMN, of Nicotinamide Mononucleotide, is a molecule that attracts attention due to its potential to promote health and longevity. NMN is a direct precursor of NAD+ (nicotinamide adenine dinucleotide), a co-enzyme that is crucial for numerous cellular processes. One of the main functions of NMN is increasing NAD+ levels in the body. NAD+ plays a central role in energy metabolism. It is involved in converting nutrients into energy, which is essential for the normal functioning of cells and organs. Without sufficient NAD+, cells cannot effectively produce energy, which can lead to reduced cell and organ function.

Additionally, NAD+ is of great importance for DNA repair. It helps in the restoration of damaged DNA, which is essential to keep genetic information intact and reduce the risk of mutations and related diseases. DNA damage occurs daily due to exposure to UV radiation, pollution, and other environmental factors, and effective repair is crucial for maintaining health.

Moreover, NAD+ contributes to the survival of cells. It plays a role in the regulation of cellular stress responses and apoptosis (programmed cell death). This is important for the removal of damaged or non-functional cells and the maintenance of overall tissue health.

The differences between NMN vs Niacin

Although both NMN and niacin play important roles in our body, they target different functions and have unique benefits and side effects. Here are the main differences between these two substances:

Chemical structure of NMN vs niacin:

NMN: 

  • NMN is a nucleotide consisting of a nicotinamide-ribose-phosphate. 
  • It is a direct precursor of NAD+, a crucial co-enzyme in energy metabolism.

Niacin: 

  • Niacin comes in two forms: nicotinamide and nicotinic acid. 
  • Both forms are converted in the body and play a role in various biochemical processes.

 

Function of NMN vs niacin:

NMN:

  • Increases the levels of NAD+ in the body.
  • Plays a key role in energy metabolism and cell survival.
  • Supports DNA repair and anti-aging processes.

Niacin:

  • Helps lower LDL cholesterol and triglycerides, and increases HDL cholesterol.
  • Supports the production of energy by converting food into usable energy.
  • Plays a role in the production of fatty acids and is involved in the health of the skin, the nervous system, and digestion.

 

Health benefits of NMN vs niacin:

NMN:

  • Improves energy metabolism.
  • Supports DNA repair and cell health.
  • Can help slow down the aging process and promote longevity.
  • Can improve cognitive function and slow neurodegenerative diseases.

Niacin:

  • Lowers LDL cholesterol and triglycerides, which is beneficial for cardiovascular health.
  • Increases HDL cholesterol, which helps remove excess cholesterol.
  • Supports the health of the skin and nervous system.
  • Contributes to digestion by stimulating the production of stomach acid.

 

Side effects of NMN vs niacin:

NMN:

  • Generally well tolerated.
  • Possible mild side effects such as stomach upset.

Niacin:

  • Can cause 'niacin flush', which means redness and itching.
  • In higher doses, it can cause liver function disorders.
  • Can cause stomach complaints and nausea in some people.

 

The relationship between NMN and niacin

Although NMN and niacin follow different biological pathways and fulfill unique functions, they share a common role. Both substances are important for maintaining optimal cell and body function and can complement each other in their action.

A key common role of NMN and niacin is their contribution to protecting cells against oxidative stress. Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body, which can lead to cell damage. Both NMN and niacin help limit this damage through their involvement in energy metabolism and the production of NAD+. 

By supporting DNA repair and promoting efficient energy metabolism, NMN and niacin play a role in maintaining healthy cells and tissues. This can contribute to slowing down the aging process and improving lifespan.

While NMN focuses on increasing NAD+ levels for energy production and DNA repair, niacin focuses on improving cardiovascular health by lowering cholesterol and supporting skin and nervous system health.

Together, these supplements can offer a holistic approach to promoting overall health and well-being. By using both NMN and niacin, one can benefit from their complementary advantages, such as improved energy levels, better skin health, and a reduced risk of cardiovascular diseases. This contributes to a better quality of life in the long term.

Which is better: NMN or niacin?

The choice between NMN and niacin strongly depends on your specific health goals. Both supplements offer unique benefits and target different aspects of health and wellness. Here are some considerations that can help in making an informed decision:

For anti-aging and energy metabolism: NMN

  • Direct increase of NAD+ levels: NMN is effective in increasing NAD+ levels in the body. By raising NAD+ levels, NMN can help improve overall cellular health and slow down the aging process.
  • Support of cell health and longevity: The role of NMN in increasing NAD+ levels makes it a powerful supplement for those focusing on anti-aging. It can help maintain healthy cells, contributing to longer lifespan and better overall health.

For cholesterol reduction and cardiovascular health: Niacin

  • Lowering LDL cholesterol and raising HDL cholesterol: Niacin has been proven effective in lowering LDL cholesterol (the 'bad' cholesterol) and triglycerides, while raising HDL cholesterol (the 'good' cholesterol). These properties make niacin particularly useful for improving cardiovascular health and reducing the risk of heart and vascular diseases.
  • Support for cardiovascular health: The cholesterol-lowering properties of niacin can help prevent plaque formation in the arteries, which is crucial for maintaining healthy blood circulation and preventing heart attacks and strokes.

Both supplements have their unique benefits and can even complement each other in a holistic approach to health and wellness. At EnduraVita you will find the highest possible pure NMN. It is always advisable to consult with a healthcare provider before starting new supplements, to ensure they fit your specific health needs and goals.

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